Although we can provide MHC class I tetramers with either human or murine b2-microglobulin, we typically fold all tetramers of every species with human b2-microglobulin. Use of murine b2-microglobulin ...

Rodents fed a diet high in soluble fiber showed improved resistance to a microorganism that causes diarrhea and can be fatal ...

Major histocompatibility complex (MHC) class I presentation of peptides to T cell receptors (TCR) on T lymphocytes is the key in the immune response. Because of their unique specificity, MHC-peptide ...

Although elegant, this model was not verified. Hybrid resistance was mapped to several putative Hh loci located close to MHC class I genes, but no corresponding genes or antigens were ever found.

Viral protein is made intracellularly and the protein is processed via the endogenous MHC class I pathway. DNA vaccines. DNA vaccines favor a cell-mediated immune response. DNA plasmid vector ...

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Finally, several studies demonstrate that NK cells, activated due to missing self-MHC class I molecules on allogeneic cells, are involved in allogeneic skin graft rejection via direct killing of ...

TCR-peptide–MHC (pMHC) class I complexes for which crystal structures have been determined (mouse 2, 2C–dEV8–H-2K b, human 3,4: A6–Tax–HLA-A2 and B7–Tax–HLA-A2) indicate a common ...

As a result, the expression of components of the so-called major histocompatibility complex class 2 (MHC-II) was increased in the intestinal epithelium. Although MHC-II is an essential molecule in ...