Another would be working on the sleep-wake cycle. The study showed a link between the MECP2 mutation and the Alzheimer's ...

MECP2 mutations are the major genetic mutation associated with Rett syndrome. Diagnosis is made via observable features, which include regression of developmental features, including language and ...

Loss of MeCP2 function causes RTT and related neurological ... suggesting that shared pathways might explain some of the similarities in the RTT and Angelman phenotypes. The candidate gene ...

Harrison Gabel and Steven Gray Kathie Bishop Renowned leaders in neuroscience, gene therapy, and translational research join ...

Rett syndrome is a devastating neurological disorder caused mainly by mutations in the MECP2 gene found on the X chromosome. The disease causes deficits in brain function that lead to behavioural ...

Our laboratory uses genetic, cell biological, and biochemical approaches to explore the pathogenesis of polyglutamine neurodegenerative diseases, the function of Math1 in neurodevelopment, and how ...