Study shows that Rett syndrome in females is not just less severe, but different
Rett syndrome is caused by mutations of the MECP2 gene located on the X chromosome. Children with Rett initially show typical ...
Nature3mon
Modifying MeCP2
Alteration in the expression of methyl-CpG-binding protein 2 (MeCP2) has been linked to a number of neurological disorders, including Rett syndrome (RTT). A recent modifier screen in flies has ...
Neurogene announces peer-reviewed publication of EXACT transgene technology
Neurogene (NGNE) announced a peer-reviewed publication on its EXACT transgene regulation technology. The preclinical ...
Nature3mon
Patients With Rett Syndrome Sustain Low-Energy Fractures
Therefore, we investigated risk factors associated with low-energy trauma and the association to methyl-CpG-binding protein 2 (MECP2) mutations. A total of 61 female patients with RTT and 122 ...
PharmiWeb4d
Preclinical success for gene control system for Rett Syndrome
Scientists have developed a new transgene control system that shows early promise for treating rare brain disorder Rett syndrome.