Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and selectively inhibits monoamine oxidase type B (MAO-B). Rasagiline demonstrates complete and selective ...

Furthermore, anti-parkinsonian medications such as monoamine oxidase B (MAO-B) inhibitors and dopamine agonists (DAs) affect ...

Specifically, 3-phenyl substitution in coumarin derivatives significantly enhanced MAO-B inhibition and increased selectivity for MAO-A, while 4-phenyl substitution is more effective for MAO-A ...