"Its function: When m6A is attached to an mRNA, it triggers the degradation of the mRNA as soon as the first proteins have been produced according to the blueprint it contains. This is ...

Reports have shown that the epigenetic modification N 6-methyladenosine (m6A) on mRNA is associated with female reproductive diseases and pregnancy-related conditions, such as preeclampsia ...

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the ...

Figure 3. Drosophila m6A pathway. (A) m6A writers and readers. (B) Mapping of m6A modifications (miCLIP track) relative to mRNA-seq identifies extensive modification in the intronic regions (CIMS, ...

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the ...

(D) Heatmap analysis from liver RNA-seq data indicated the mRNA expression level of the m6A family after ConA treatment for 8 h. (E, F) Heatmap analysis from the GEO database showed the fold ...

Get Instant Summarized Text (Gist) A novel class of zwitterionic phospholipids, specifically DOPE-Cx, significantly enhances mRNA delivery by facilitating endosomal escape, a major challenge in ...