Although accumulating evidence showed close correlation among PPARγ, macrophages and lipid metabolism, how post-translational modifications of PPARγ in macrophages regulate adipose issue remains ...

Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization. Nature Immunology , 2018; DOI: 10.1038/s41590-018-0108-0 Cite This Page : ...

The iDLs can be either pro-inflammatory lipids that promote the M1 macrophage phenotype or pro-resolving lipids that promote the M2 macrophage phenotype, depending on which pathways are most active.

The iDLs can be either pro-inflammatory lipids that promote the M1 macrophage phenotype or pro-resolving lipids that promote the M2 macrophage phenotype, depending on which pathways are most active.

Exosomal PGE2 from M2 macrophages inhibits neutrophil recruitment and NET formation through lipid mediator class switching in sepsis. Journal of Biomedical Science 30 (62). doi: 10.1186/s12929-023 ...

EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth. Cancer Discovery , 2024; OF1 DOI: 10.1158/2159-8290.CD-23-0434 Cite This ...

Sasanka Ramanadham, Ph.D., and researchers published “Selective Reduction of Ca2+-Independent Phospholipase A2β (iPLA2β)-Derived Lipid Signaling from Macrophages Mitigates Type 1 Diabetes ...

This work is surprising in that it fingered a protein known from lipid metabolism as a regulator of macrophage-mediated inflammation. This raises the question of whether the macrophage component in ...

More information: Alexandra Kuhlmann-Hogan et al, EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth, Cancer Discovery (2024 ...