Dicer also processes long dsRNA molecules into small interfering RNA (siRNA) duplexes. Only one strand of the miRNA:miRNA* duplex or the siRNA duplex is preferentially assembled into the RNA ...

siRNAs are 21-25 nucleotide dsRNA molecules that are perfectly complementary to their target mRNA. They are derived from long dsRNA precursors, which can be produced endogenously or introduced ...