It acts as a small molecule inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), which binds to a novel pocket in the PCSK9 C-terminal domain that does not affect the PCSK9-LDL receptor ...

By Vijay Kumar Malesu Study deciphers the molecular handshake between LDL receptors and apoB100, shedding light on cholesterol metabolism and its role in cardiovascular disease. Study: Structure of ...