IFNγ-induced NO requires expression of IRF-1, a transcription factor. LPS stimulated macrophages also upregulate their surface expression of CD40, independently of TNF. IFNγ-induced CD40, however, is ...

During the same time, DCs were pulsed with α-GalCer (100 ng/ml) in the presence of LPS (100 ng/ml ... phycoerythrin (PE)-conjugated anti-CD40, anti-CD80, anti-CD83, anti-CD86, anti-human ...

In June 23 Lancet, Richard Phipps and colleagues from University of Rochester Cancer Center, Rochester, New York, suggest that these febrile responses could be due to the release of CD40 ligand from ...