Next, the researchers tried treating the mice for three months with L-DOPA, a drug typically used for Parkinson's disease. They found that the drug helped reduce plaques, elevate neprilysin levels ...

A stem cell–based therapy initially developed at Memorial Sloan Kettering Cancer Center (MSK) may lead to a new treatment for advanced Parkinson's disease, according to results from a phase 1 clinical ...

Previous studies in a rat model of Parkinson disease (PD) have shown that dyskinesia induced by L-DOPA—a treatment-limiting adverse effect of long-term administration—is caused by the release ...

The 135-subject study involved people who had at least two hours per day of off time even though they were stabilised on L-DOPA therapy. At the highest dose tested, CVN424 improved the off time by ...

However, nicotine may modulate dopamine transmission and has clear motor effects when associated with L-DOPA, reducing L-DOPA-induced dyskinesias. Clinical trials have yielded inconclusive results ...

Highlighting advancements in treatment, Dr Nishit Sawal emphasized the role of Liquid Carbidopa Ascorbic Acid Solution, a ...