Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.

Blood cancer patients who receive a type of anti-cancer therapy should continue to take the drug while having COVID-19 ...

Researchers have unveiled a novel immune mechanism by which tandem kinases combat pathogen invasion: an atypical NLR protein, ...

No association was observed between serious infection risk and Janus kinase inhibitor use in patients with immune-mediated inflammatory skin disease.

Here, the kinase partners with TOM and VDAC, forming a supersized complex that tethers PINK1 to the outer membrane—a crucial first step toward clearing these defective organelles. The study appeared ...

The off-label use of JAK inhibitors to treat JDM is common in pediatric rheumatology, with barriers to use including limited clinical trial data and insurance approval.

What Is Mevalonate Kinase Deficiency? Mevalonate kinase deficiency (MKD) is a disease that runs in families. A problem with your immune system causes attacks of fever and symptoms like swollen ...

A research team led by Prof. LIU Zhiyong from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, together with collaborators, has uncovered a novel immune ...