In a recent preclinical study published in the Journal of Clinical Investigation, researchers in the United States of America investigated the role of the transcription factor KLF15 (short for ...

They found that the abundance of transcription factor KLF15 increased in skeletal muscle of diabetic mice, and mice that lack KLF15 specifically in muscle were resistant to diabetes-induced ...

Febraury 24, 2012 (Cleveland, Ohio) — Researchers have identified a molecule that links circadian rhythms to ventricular arrhythmias in an animal model, with the results providing a greater ...

Now they have found a new benefit of Kruppel-like Factor 15 (KLF15) — keeping the body in metabolic balance. The discovery, which highlights how KLF15 affects the availability of nutrients in the body ...

"We hypothesized that maybe the absence of Klf15 or its relative deficiency might be unhealthy, so we generated mice to mimic this," Jain explains. The mice, which were completely deficient in ...

“Strikingly, we found that the expression level of Klf15 is approximately 75% lower in brown adipose tissue (BAT) than in white (WAT),” they wrote. “These results suggest physiological ...

The protein called kruppel-like factor 15 (Klf15), which was controlled by the body clock and whose levels in the body went up and down during the day was detected. Genetically modified mice which ...

The finger points at levels of a protein called Klf15, they said. Previous research has found Klf15 to be a circadian controller - and, startlingly, is also lacking among some patients with heart ...

They found that the abundance of transcription factor KLF15 increased in skeletal muscle of diabetic mice, and mice that lack KLF15 specifically in muscle were resistant to diabetes-induced ...