Two new studies from MIT and Harvard Medical School, focusing on a cytokine called IL-17, now add to that evidence. The researchers found that IL-17 acts on two distinct brain regions—the ...

UCB has been bringing up the rear in the IL-17 inhibitor category with bimekizumab, but now has EU approval for the drug and thinks it can mount a stiff challenge to the leaders, including ...

Belgian biopharma company UCB is bringing up the rear of the IL-17 inhibitor category with its bimekizumab drug, so is celebrating new late-stage data showing superiority to the class leader.

Researchers from Protagonist Therapeutics Inc. reported the preclinical characterization of PN-881, an oral macrocyclic peptide that inhibits the dimeric forms of IL-17 – AA, AF, and FF.

Ascletis Pharma Inc. has announced IND clearance by the FDA for a phase I trial of ASC-50 for the treatment of mild to moderate plaque psoriasis. Dosing is expected to start in the third quarter of ...

“The exact link between IL-17 inhibitors and IBD remains unclear, and no causal relationship has been established, but it may involve IL-17’s protective role in the gastrointestinal tract ...

In a 2019 study in mice, Choi and Huh showed that in some cases of infection, IL-17 is released and suppresses a small region of the brain's cortex known as S1DZ. Overactivation of neurons in this ...