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The human immune system is highly complex and well-equipped to combat most bacteria. However, in some instances bacteria can cause life-threatening infections and the increase of antibiotic-resistant ...
which is a CD20 x CD3 bispecific IgM antibody designed to treat patients with B cell Non-Hodgkin's lymphoma and other B cell malignancies, IGM-8444, which is an IgM antibody targeting Death ...
IGM Biosciences (NASDAQ ... is considerably larger than its abandoned oncology efforts, data for T cell engagers (TCEs) in autoimmune diseases is still very nascent, and physicians we have spoken ...
An IGM news release from Jan. 9 shed more light ... CEO Dr. Mary Beth Harler wrote that “the depth and consistency of B cell depletion is insufficient to meet our high bar for success.” ...
Cross-linking Fcα/μR expressed on a pro-B cell line Ba/F3 transfectant with soluble IgM or IgM-coated microparticles induced internalization of the receptor. Fcα/μR also mediated primary B ...