Published in the peer-reviewed journal mAbs, the study presents nipocalimab's high-affinity binding to the neonatal Fc receptor (FcRn) and its capability to significantly reduce IgG levels ...

Mårtensson, L., Proc. Eleventh Cong. Intern. Soc. Blood Transf., Sydney 1966, Bibl. Haemat., No. 29, Part 2, 510 (Karger, Basel and New York, 1968).

Firstly, the attachment site on a specific amino acid within the antibody IgG-Fc framework means the antibody maintains almost the same performance when part of the ADC. Otsuka breaks up with ...

J&J exhibited additional findings from the Vivacity-MG3 study, displaying that nipocalimab met its key secondary endpoint.

Although the polymeric immunoglobulin receptor ... Azuma, Science University, Tokyo), and human IgM-Fc (Rockland, Gilbertsville, PA) were used. Monoclonal antibodies to human CD3, CD45 and ...

S-1117 is a novel engineered Fc-fused pan-IgG protease targeting IgG autoantibodies, and S-4321 is a non-depleting bifunctional PD‑1: FcγRIIb‑selective agonist antibody for the treatment of ...