Systemic inhibition of interleukin (IL)-1 with rilonacept (IL-1 Trap ... reduced in response to pharmacological blockade of the IL-1 pathway. To further explore the consequences of IL-1 blockade ...

most commonly drugs that target the interleukin-1 (IL-1) pathway including anakinra (Kineret) and canakinumab (Ilaris) -- unlike in other forms of inflammatory arthritis in which tumor necrosis ...