we have identified here a molecule we call interferon-β promoter stimulator 1 (IPS-1). Overexpression of IPS-1 induced type I interferon and interferon-inducible genes through activation of IRF3, ...

Four hundred eighty-eight patients were randomly assigned to five treatment groups: DTIC+IFN-α+Tα1 (1.6 mg); DTIC+IFN-α+Tα1 (3.2 mg); DTIC+IFN-α+Tα1 (6.4 mg); DTIC+Tα1 (3.2 mg); DTIC+IFN-α (control ...

Interferon-free sustained virologic responses ... and differential responses for the genotype 1 subtypes 1a and 1b have emerged with many DAA combinations. Viral breakthrough and resistance ...

Our findings indicate that APS-1, which is caused by AIRE deficiency, is characterized by excessive, multiorgan interferon-γ–mediated responses. JAK inhibition with ruxolitinib in five patients ...

1 and BA.5, and their efficacy in protecting cells from influenza A virus super-infection. Interferon signaling has been shown to play an important role in determining the severity of coronavirus ...

Overall survival in the combination-therapy group did not differ significantly from that in the interferon group (hazard ratio, 0.96; 95% CI, 0.76 to 1.20; P=0.70). Median overall survival times ...

Laboratory data are summarized in Table 1. Chest radiography revealed pulmonary ... patient's cardiomyopathy was considered likely to be interferon administration, although other etiologies ...

There are three basic forms of interferon. These are alpha and beta, also known as type 1, while gamma is known as type 2. Each form of interferon has different effects on the body. Share on ...