Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are ...

In Mycobacterium abscessus complex pulmonary disease, elevated levels of IFN-γ and IL-17F may signal higher risk for disease ...

For example, activated T helper type 1 lymphocytes secrete interferon (IFN)-γ, which has potent effects on osteoclastogenesis in vivo and in vitro. IFN-γ, however, is known to cause both bone ...

Malaria’s hidden threat to breastfeeding mothers An expert explains how it harms breast health reduces milk supply and what ...

GEN-1013 was studied in an aggressive CT26 murine cancer model using both IT and IV administration.Significant tumor reduction was observed in both administration routes. Both IT and IV were ...

A significant discovery has identified a missing "gatekeeper" protein as the root cause of dry mouth in Sjögren's syndrome — a finding that could change the way the disease is treated.

The cytokine IFN-γ is known to be essential to induce the tumor-killing capacity of T cells. Additionally, an alternative metabolism called glycolysis, which is able to produce energy in human ...

Scientists have identified tricellulin loss as the root cause of dry mouth in Sjögren's syndrome, and successfully reversed ...

Figure 1: IFN-γ capture assay enriches tumor-reactive T cells from immunized mice. Figure 3: IFN-γ capture assay detects and enriches tumor-specific T cells from human RCC. In conclusion ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...