particularly the type I IFN pathway, which is known to play a role in innate immune responses and bone formation. A single-cell transcriptome profiling study has identified the activation of type ...

“These data support the future development of a standardized clinical test to measure IFN pathway activation as a biomarker of disease activity in patients with diffuse cutaneous systemic ...

The level of IFN-β induction by cGAS was similar to that of MAVS when ... this finding solidified its place as the elusive cytosolic DNA sensor to complete the cGAS-cGAMP-STING pathway. “It was quite ...

In Mycobacterium abscessus complex pulmonary disease, elevated levels of IFN-γ and IL-17F may signal higher risk for disease ...