They do so by using MHC-II to instruct a different subset of CD4 + T RM cells in the airways to produce a cytokine IFN-gamma, ...

Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are ...

By performing an integrative analysis with public datasets, they identified MHC class II genes ... Their findings revealed that IFN-γ signaling activation and ERK/MAPK signaling inactivation ...

In mice with MHC class I-negative tumors ... in a substantial increase in both NK cell cytolytic activity and IFN-γ production. Thus, DC are involved in the interaction between innate and ...

High serum type I interferon (IFN) scores, measured through six chemokines, correlated with poorer lung function and health-related quality of life in patients with diffuse cutaneous systemic ...

Figure 1: IFN-γ capture assay enriches tumor-reactive T cells from immunized mice. Figure 3: IFN-γ capture assay detects and enriches tumor-specific T cells from human RCC. In conclusion ...