Interferon (IFN) has been shown to have antiviral, antiproliferative, and immunomodulatory effects, all of which may be important in HBV therapy. Thus, IFN increases cytotoxic T-cell immune ...

[92] Summary of hepatitis B e-antigen (HBeAg) seroconversion at 1 (a) and 2 years (b) in patients receiving different treatment. For pegylated interferon (peg-IFN)-treated patients, the HBeAg ...

The trial demonstrated that six doses of imdusiran and 24 weeks of IFN led to a functional cure in 50% of HBeAg-negative patients with baseline hepatitis B surface antigen (HBsAg) levels below ...

Peginterferon alfa-2a is a form of recombinant interferon already indicated to treat chronic hepatitis B infection in people who show signs of liver damage. "Combining drugs with different target ...

HBV’s morbidity arises in part from its ‘stealth ... provide benefit when paired with VIR-2218. • VIR-2218 with PEG-IFN-α: PEG-IFN-α is currently the only approved treatment shown ...

An in-depth look at Hepatitis D, why it’s so severe, and how new therapies bring hope for better treatment and prevention.

Test for HBV infection prior to initiation ... if previously treated with regimens containing PEG-IFN, ribavirin, and/or sofosbuvir, but no prior treatment with an HCV NS3/4A protease inhibitor ...