Bile is a body fluid produced by the liver that has a digestive and an excretion function. Bile could collect disease biomarkers released from the biliary tract or surrounding tissues, such as the ...

By identifying new bile acid metabolites, we are piecing together how these compounds interact with various cellular systems, including the gut microbiome, to affect human health and disease. This ...

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. When this ...

Using the improved technique, McCurry found that certain glucocorticoids are more abundant in human bile than others. The authors were most intrigued by a group of glucocorticoids that that could be ...

A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of ...

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

EPFL scientists have uncovered how a gut bacterium, Clostridium scindens, aids in healing intestinal injuries by restoring bile acid balance. Their findings could pave the way for new treatments for ...

Analysis of human fetal gallbladder bile provides a more direct assessment of primary hepatic synthesis in utero, but only limited studies have been described. Using HPLC, GLC and mass ...

Study findings indicate therapeutic potential of microbiome-based intervention to restore bile acid balance and promote gut healing in ulcerative colitis.

examined the effects of bile acids on energy expenditure in mice, and in cultured mouse and human cells. The team found that administering cholic acid—a bile acid—to mice on a high-fat diet ...