These events are associated with innate training and can have long-term impacts on hematopoietic stem and progenitor cell (HSPC) development but can also compromise their function. While many ...

These findings suggest that late-stage WNT inhibition not only remodels their transcriptome to more closely resemble bona fide hematopoietic stem cells but also enhances HSPC differentiation and ...

ARLINGTON, VA — Arlington Tech, Governor's STEM Academy Computer Science program and the Arlington Career Center hosted APS HSPC, the first programming competition for middle and high school ...

The findings enhance our understanding of HSPC development and may inspire new strategies for regenerative medicine and treatments for blood disorders. More information: Xiaohan Wang et al ...

In this study, we focused on murine bone mesenchymal stem cells (MSCs ... We separated the HSPC niche gene set into two groups: the upregulated niche genes and the downregulated niche genes.