Heat shock protein 90 (HSP90) is a molecular chaperone of numerous oncoproteins. Therefore, cancer cells can be considered to be 'addicted' to this molecule. HSP90 is also a mediator of cellular ...

Heat-shock protein 90 (Hsp90) is a molecular chaperone that is important for the maturation, stability and activity of numerous cancer-related proteins. Hsp90 is frequently overexpressed and ...

JIN-001': An Innovative New Drug Targeting Refractory Ovarian Cancer Also presented was 'JIN-001,' J INTS BIO's second-generation synthetic HSP90 inhibitor, developed as a new strategy to overcome ...

Hsp90 signaling and its inhibition in cancer The evaluation of Hsp90 as a therapeutic target in cancer patients is another major focus of our lab. Hsp90 is a chaperone required for maintaining the ...

Presently, I am working under the supervision of Prof. Gabriela Chiosis on the functions of the hyperconnected HSP90 protein networks called “epichaperome” in cancer cell survival. Disruption of the ...

J INTS BIO, a company specializing in anticancer and orphan drugs, announced its research findings for the next-generation ...