A team of researchers led by Prof. Xiao Jun from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese ...

Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4. The chain of nucleosomes is then wrapped into a 30 nm spiral called a solenoid, where additional ...

A research team has unveiled a crucial mechanism that helps regulate DNA damage repair, with important implications for ...

This post-translational modification stabilizes RNF168, enhancing its recruitment to damage sites, which amplifies downstream ubiquitination of histone H2A/H2AX and ultimately promotes DNA repair.

What happens if you shake the worms? Australians Ivan Maksymov and Andriy Pototskyy among the winners of Ig Nobel Prize ...

NHK has learned that Japan plans to launch the country's flagship H2A rocket for the 50th and last time early in the morning on June 24, local time. The H2A will be completely replaced by the H3 ...

The basic organizational unit of the genome is a nucleosome, which is a short segment of DNA wound around a complex of eight histone subunits. Each of these histones has a tail region which can be ...

In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various ...