The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

DNA methylation and histone modification influence each other during development. Histone methylation can help to direct DNA methylation patterns, and DNA methylation seems to serve as a template ...

Can autism symptoms be reversed after brain development? A new JNCASR study suggests it might be possible with a sugar-linked ...

In a preprint uploaded to bioRxiv this January that has yet to undergo peer review, the team describes hundreds of potential histone proteins in bacteria, including one that they predict interacts ...

A research team led by Dr. Li Yunhai from the Institute of Genetics and Developmental Biology of the Chinese Academy of ...

Eight months after announcing the $18.5 million first tranche of its series A, Augustine Therapeutics has closed the oversubscribed round at $85 million and is now ready to begin clinical development ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

Epigenetic modifications, particularly histone covalent modifications, play a crucial role in regulating plant growth and environmental responses. Among these, histone H3 lysine 27 trimethylation ...

Schematic representation of histone-modifying factor recruitment on cccDNA minichromosomes in relation to viral protein HBx. GA, UNITED STA ...

LSD1 is a histone demethylase that plays a significant role in chromatin remodeling and gene expression by modifying histone H3 lysine residues. It interacts with various protein complexes ...