Northwestern Medicine investigators have discovered how disruptions in the circadian rhythm in our muscles combined with poor ...

In short, this study shows that poor sleep and poor diet can create the perfect storm for developing diabetes—not because you ...

With the final step in HIF pathway established, scientists began to explore ways to utilize it. Because the hypoxia response is present across all tissues and cell types, the HIF pathway drives ...

Munich news, health insurance, technology, jobs and other topics for expatriates. The Eye Newspapers covers daily news and offers services for foreigners.

Mechanistically, hypoxia initiates inflammation through the hypoxia-inducible factor-1 (HIF-1) pathway-mediated expression of interleukin-1beta (IL-1β) and tumor necrosis factor-alpha (TNF-α).

DMR-genes found in HIF-1 signaling pathway. These DMRs is found between Tibetan and other three ethnics. Genes with DMR are marked with blue color.

One host-genetic pathway that I have previously identified as being a modulator of both inflammation and infection is the HIF pathway, an important cellular oxygen sensing pathway. In the normal ...