Hematopoietic stem cell gene therapy (HSC-GT) represents a cutting-edge treatment strategy for multiple genetic disorders. By correcting genetic defects within hematopoietic stem cells (HSCs ...

"For the first time, our study showed that producing disordered proteins and maintaining the structural diversity of the ...

An Osaka Metropolitan University-led study demonstrated that Cdc42 (cell division cycle 42) plays a crucial role in the formation and maintenance of the morphological characteristics of quiescent ...

Cellistic has launched the Echo-NK platform to enable the scalable manufacturing of allogeneic cell therapies to target multiple diseases.

Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells (MSCs) — are the common predecessors of cells of the mesenchymal lineage, such as bone, cartilage and fat ...

We discovered that interferon gamma (IFNγ) promotes hematopoietic stem cell (HSC) division and myeloid differentiation in a mouse model of Mycobacterium avium infection (Nature 2010). Furthermore, ...

Cellistic, a pioneer in induced pluripotent stem cells (iPSC)-based cell therapies, is launching the Echo™-NK platform to enable the scalable manufacturing of allogeneic cell therapies to target ...

To ensure continuous blood cell production is necessary to preserve hematopoietic stem cells (HSC) in a resting state while preserving their capacity to differentiate on demand into different blood ...