In an article published in Nature Cancer, a multi-institutional research team led by the University of Osaka describes how a molecule called HLA-DRB1 can be used as a target for chimeric antigen ...

The risk of MS is significantly higher in people with a specific gene variant called HLA-E*01:01 and a history of mono, a study found.

A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments. The team ...

These results confirm the association between antibiotic-refractory Lyme arthritis and HLA-DRB1 molecules that bind to OspA 163–175. The authors conclude that the binding of this peptide to ...

These mice expressed the human leukocyte antigen (HLA) allele (DRB1*15:01) instead of the mouse version of the same allele, which codes for the proteins that display foreign antigens on the surfaces ...

The Glasgow team also looked for potential causative factors in the children themselves, finding that 89 percent of the children with acute hepatitis—but only 16 percent of Scottish children in ...

Using a sequencing strategy, the researchers determined that KG2032 bound to HLA-DRB1. "Interestingly, we found that KG2032 reacted with a specific HLA-DRB1 subset in which the protein has an ...