More information: Shunya Ikeda et al, CAR T or NK cells targeting mismatched HLA-DR molecules in acute myeloid leukemia after allogeneic hematopoietic stem cell transplant, Nature Cancer (2025).

In a recent article published in Nature Cancer, a multi-institutional research team led by The University of Osaka describes how a molecule called HLA-DRB1 can be used as a target for chimeric antigen ...

We did a series of co-precipitation experiments with arthritis-predisposing and neutral DR alleles and looked for the association of HSP73. Co-precipitation of HSP73 with HLA-DR was observed in ...

or HLA class II type (HLA-DR, -DQB, -DQA and -DP antigens). The specificity assay based on flow cytometry contains a panel of 55 HLA class I beads and 32 HLA class II beads. The majority of HLA ...

A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments. The team ...

marking a significant milestone for both Dr. Huang and the entire HLA department. This prestigious recognition represents Purdue’s highest teaching accolade for faculty members in the early stages of ...