The risk of MS is significantly higher in people with a specific gene variant called HLA-E*01:01 and a history of mono, a study found.

BOSTON, MA, UNITED STATES, April 24, 2025 /EINPresswire.com/ -- Affini-T Therapeutics to present data from pipeline programs targeting the cancer driver mutations KRAS G12V and TP53 R175H.

One exception to this trend relates to the human leukocyte antigen (HLA) gene cluster on chromosome 6p21.3, which was discovered to be an MS susceptibility locus in the early 1970s through use of ...

The utility of HLA typing as a diagnostic and/or predictive test for these potentially life-threatening reactions depends on the veracity of the genetic association, the clear phenotyping of the ...