Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) and protease, the molecular targets of anti-retroviral drug therapy, are prime examples of genes in which ...

As sequencing technology and prediction algorithms improve, HIV genotyping and coreceptor usage prediction are likely to play an increasingly important role in guiding patient prognosis and ...

An immune protein previously thought to mark inactive T cells has a free-floating form that correlates with HIV disease progression. Sequencing HIV integration sites suggests that clonally expanded ...

Khalili and his team further perfected their technique by only inactivating MOGS in infected immune T cells using an HIV-specific promoter sequence. “We wanted to make sure that the manipulation of ...

Traditional measures of genetic diversity (summary statistics and coalescent estimators) have helped to understand HIV diversity and distribution. Next-generation sequencing is providing a new ...

A block to more potent and specific release of HIV from latency has been identified as a subunit of the Integrator complex, which may aid strategies for HIV cure.

Traditional measures of genetic diversity (summary statistics and coalescent estimators) have helped to understand HIV diversity and distribution. Next-generation sequencing is providing a new ...