A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible ...

Because RNAs are so central to our biology, they are also drivers of a wide array of diseases. Defects in how RNA is produced ...

No significant association was observed between viremia history during ART and CVD risk in a large international cohort of patients with HIV infection.

They graphically represent the life cycle of HIV-1, from the initial binding of ... cell's nucleus to spark the formation of new viral RNA strands (Viral Gene Transfer), and finally to the ...

A viral load result is usually described in terms of the number of HIV RNA copies per millilitre of blood (copies/ml). Because the actual copy numbers can span up to the hundreds of thousands and ...

To study pathogenesis and develop vaccines, it would be desirable to use infectious HIV and SIV clones derived from plasma viral RNA, which is more representative of the replicating virus pool ...

Although DNA is the primary genetic material of cells, RNA is the genetic material for some viruses like HIV. A protein substance (immunoglobulin) produced by the immune system in response to a ...

The primary endpoint was the percentage of participants with < 50 copies/mL of HIV-1 ribonucleic acid (RNA) at week 48. “These findings provide evidence that resistance testing might not be a ...

At 48 weeks, 98% of patients with HIV and initial viremia on long-acting ART achieved viral suppression, supporting updated ...

Furthermore, this method can be expanded to capture HIV RNA in the same cell. “ECCITE-seq allows us to tackle the heterogeneity, rarity and the lack of marker in these cells, which is very ...

A block to more potent and specific release of HIV from latency has been identified as a subunit of the Integrator complex, which may aid strategies for HIV cure.