A significant proportion of patients undergoing atrial fibrillation (AF) ablation as part of the CABANA trial had a high probability of heart failure with preserved ejection fraction (HFpEF).

Understanding how patients with heart failure with preserved ejection fraction (HFPEF) die provides insight into the natural history and pathophysiology of this complex syndrome, thereby allowing ...

Novartis was expecting a lot from its PARAGON-HF trial of Entresto in heart failure with preserved ejection fraction (HFpEF) and isn’t letting a missed endpoint scupper the programme.

Heart failure with preserved ejection fraction (HFpEF) is a disease in which the left ventricle (LV) of the heart shows impaired relaxation during cardiac diastole, often accompanied by structural and ...

When we examined the Phase 1b data for TX45, several things stood out to us. Specifically, in 16 HFpEF patients, pulmonary capillary wedge pressure fell by 17.9%, pulmonary vascular resistance ...

Heart failure with preserved ejection fraction, or HFpEF, occurs when the heart pumps normally but is too stiff to fill properly. Current research suggests that HFpEF occurs when chronic medical ...

The clinical benefits of tirzepatide in patients with HFpEF and obesity were consistent regardless of kidney function. The effect of tirzepatide on kidney function depends on how CKD is defined ...

HFpEF is a type of heart failure in which the left ventricle becomes stiff and does not properly fill with blood, reducing the body's ability to effectively pump blood with each heartbeat. The ...

Previous studies have shown improved kidney function with other drugs in the same class but this trial is the first to assess tirzepatide's impact on kidney and cardiovascular outcomes in people ...

The drug tirzepatide improved kidney function and cardiovascular outcomes among patients with obesity and heart failure with preserved ejection fraction (HFpEF) compared with placebo at one year ...

It’s especially vital for spotting Heart Failure with preserved Ejection Fraction (HFpEF) — now over half of all heart failure cases — and for monitoring cardiotoxicity in oncology patients ...