Only a small proportion of patients with preclinical left ventricular diastolic dysfunction develop HFpEF over time, with ...

Results from MUSIC-HFpEF Phase 1/2a clinical trial show favorable safety profile and early clinical benefits with SRD-002 ...

A study led by a physician-scientist at the University of Arizona College of Medicine–Tucson's Sarver Heart Center identified ...

The role of ACE inhibitors in the management of HFPEF is less significant compared with their role in the management of heart failure with left ventricular systolic dysfunction. For patients with ...

OMRF’s Kamil Kobak earned a $231K AHA grant to study the link between muscle loss and a common, deadly heart condition.

The complete data from Part A of the Phase 1b clinical trial confirmed the tolerability and hemodynamic effects of TX45 in patients with PH-HFpEF previously reported in the interim data.

In about half of cases, the muscle is weak and has difficulty pumping. The rest result from a stiff muscle, a type called heart failure with preserved ejection fraction, or HFpEF. The research team ...

“Now, these data, in combination with the STEP-HFpEF program, are really building this case that there's not just improvements in ‘function and feel’ endpoints, but really there’s this clinical ...

When we examined the Phase 1b data for TX45, several things stood out to us. Specifically, in 16 HFpEF patients, pulmonary capillary wedge pressure fell by 17.9%, pulmonary vascular resistance ...

ZyVersa Therapeutics Heart failure with preserved ejection fraction (HFpEF), a chronic inflammatory condition, is a leading cause of morbidity and mortality globally. Obesity, diabetes, and ...