Platelets isolated from HFD-fed mice also exhibited greater fibrinogen adhesion, spreading, and aggregation. Tumor-bearing mice consuming a HFD exhibited a greater concentration of platelets in ...

The study demonstrated that male mice fed a high-fat diet (HFD) to induce obesity had increased neutrophil numbers. Additionally, the neutrophils present exhibited the markers of either immature ...

Metabolic dysfunction-associated steatotic liver disease (MASLD), is the most common form of chronic liver disease worldwide. This study aimed to ...

Preclinical trials using mice fed a high-fat diet (HFD) revealed additional benefits. HPH-15 not only improved insulin sensitivity but also lowered blood glucose levels from 11.1 mmol/L to 8.2 ...

Mice were divided into two groups: one was fed a regular diet comprising 4% fat (REG), while the other was given free access to both regular and high-fat food, containing 60% fat (HFD).

(A–H) Western blots and quantitative PCR were performed to analyze IRF8 levels in the livers of C57BL/6J male mice fed with HFD or CD (A, B) (n = 5 biologically independent mice), lean or ob/ob ...

C57BL/6J male mice treated with AAV-IRF8 or AAV-GFP fed on HFD (n = 8 biologically independent mice from two groups), and (F, G) C57BL/6J mice treated with AAV-shIRF8 or AAV-GFP fed on HFD.

The studies showed that treatment with opaganib markedly suppressed weight gain in mice fed the HFD but not in mice given the control diet (CD). Compared with mice given CD, mice on the HFD ...

Li sought to investigate how different kinds of fat affect obesity and obesity-related tumor growth. So, he fed some mice a high-fat diet containing lots of fish oil while others received a high-fat ...