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CKD is focusing on AF due to evidence that cardiovascular disease induces HDAC6 expression and thereby reduces tubulin acetylation. In preclinical animal studies, CKD-510 restored tubulin ...
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Augustine secures $85m to advance Charcot-Marie-Tooth candidateAugustine’s approach focuses on inhibiting the cytosolic histone deacetylase 6 (HDAC6) enzyme, which plays a key role in neurodegeneration and aging-related cellular processes. The company’s ...
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