New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

The new research helps explain how these memories are formed and held so strongly in the brain. The scientists found that HDAC5, an enzyme that controls how genes are turned on or off, plays an ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

The paper Y. Cho et al., “Injury-induced HDAC5 nuclear export is essential for axon regeneration,” Cell, 155:894–908, 2013. To regenerate after injury, a nerve cell must turn on gene programs that ...

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New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity ...

N ew research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity ...

Research published in Biological Psychiatry uncovers the critical role of the HDAC5 enzyme in the gene expression of drug use relapse triggers, uncovering a new molecular target for the ...

Research published in Biological Psychiatry uncovers the critical role of the HDAC5 enzyme in the gene expression of drug use relapse triggers, uncovering a new molecular target for the development of ...