This Review focuses on the family of histone deacetylases (HDACs) and their regulatory roles in cells with specific application to neurons. It presents a structure–function analysis of four HDAC ...

Interestingly, HIF-1-alpha overexpression is mediated by histone deacetylases, especially HDAC2. Preclinical studies suggest that HDAC2 inhibition can suppress tumor cell migration and downregulate ...