Figure 3: The Dnmt1-interacting region of HDAC1 associates with methyltransferase ... Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915–926 ...

PRMT1, arginine methyltransferase 1; CBP, CREB binding protein; HDAC1, histone deacetylase 1 ... the persistence of covalently closed circular DNA (cccDNA), which serves as a viral reservoir.

Now, a photoswitchable DNA structure-specific ... activity relationships that promote this transformation. LSD1-CoREST-HDAC1/2 complexes are degraded by both the drug UM171 and cancer-associated ...