It presents a structure–function analysis of four HDAC classes, the NAD +-independent and NAD +-dependent enzymes, subcellular localization, and substrates for deacetylation. Furthermore ...

Antoinette S. Perry; R. William G. Watson; Mark Lawler; Donal Hollywood The final two classes of HDAC inhibitors consist of the electrophilic ketone, trifluoromethylketone, and the miscellaneous ...