It presents a structure–function analysis of four HDAC classes, the NAD +-independent and NAD +-dependent enzymes, subcellular localization, and substrates for deacetylation. Furthermore ...

He has been principal or sub-investigator in over 135 academic and industry-sponsored phase I trials, including of inhibitors of HDAC, AKT, the alpha-folate receptor, Hsp90 and Chk1. At any one time, ...