The addition of post-transplant cyclophosphamide to sirolimus and cyclosporine reduced chronic GVHD. Efforts are needed to optimize cyclophosphamide dose to reduce toxicity. A novel regimen ...

The regulator has cleared Ryoncil (remestemcel-L) to treat steroid-refractory acute GVHD in paediatric patients aged two months and older. It is derived from MSCs harvested from the bone marrow of ...

To manage GvHD, clinicians administer immunosuppressants ... from CRS and/or T cell migration to the central nervous system (CNS)). Previous research has shown that the disappearance of CAR ...