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These systems, which the researchers call TIGR (Tandem Interspaced Guide RNA) systems, use RNA to guide them to specific ...

With this level of control, scientists can fine-tune how nanomedicines interact with the human body. These new designs are ...

an RNA molecule that can act as an enzyme to catalyze RNA splicing inside a cell, into two inactive pieces. Scientists at ORNL then attached the ribozyme pieces to guide RNA sequences designed to bind ...

Editing RNA isn’t all that different from DNA base-editing techniques, which typically use Cas9 or other enzymes attached to a CRISPR guide RNA to replace one nucleotide with another. In the case of ...

For discussion questions and lesson plans, go to the RNA Lab collection on PBS LearningMedia. The standards-based NOVA RNA Lab allows users to explore the science of RNA and learn how to design ...

Scientists realized that they could edit and disrupt gene function in eukaryotes by engineering customizable short guide RNA to direct the enzymes to introduce cuts at specific points in the genome.

What if you could create a molecular machine that might one day help save someone’s life—just by playing a game? Well, you actually can. NOVA’s RNA Lab is an extension of a game called ...

Our investigations of exosomes in budding yeast revealed that its central channel is essential, and that it functions to guide RNA substrates to the active sites of both Dis3 and Rrp6. We subsequently ...