Tuberculosis, the world's deadliest infectious disease, is estimated to infect around 10 million people each year, and kills ...

The paper, titled "An enzyme-proof glycan glue for extracellular matrix to ameliorate intervertebral disk degeneration," is published in Nature Communications, The research team screened the Human ...

Several glycan-masked mutants showed significantly decreased antibody binding to non-CD4bs “off-target” epitopes while maintaining strong binding to CD4bs-specific bnAbs. Furthermore ...

GlycoNex, Inc. (4168, hereinafter referred to as GNX), a clinical stage biotechnology company focused on the development of glycan-directed cancer immunotherapies, today announced the presentation of ...

Alphamab has developed JSKN021, a dual payload bispecific ADC targeting EGFR/HER3, utilizing glycan-specific conjugation technology. The novel DNA topoisomerase I inhibitor T01 and the microtubule ...

For the creative use of chemistry-centred tools to provide valuable insights into glycan biology. Collectively, the field is getting to a point where we will be able to study complicated biological ...

MIT chemists have now overcome that obstacle, demonstrating that they can label a glycan called ManLAM using an organic molecule that reacts with specific sulfur-containing sugars. These sugars ...