Diabetes. 2006;55(1):1-12. Glucokinase is required for GSIR in the physiological range of 4-8 mmol/l. Glucokinase is needed for amino acid and fatty acid stimulation of insulin release.

Magnesium regulates an enzyme known as glucokinase, responsible for converting glucose into glucose-6-phosphate. Type 2 ...

The Mendelian Randomization studies of human genetic data provided scientific evidence to support the exploration of glucokinase activation in diabetic complications and new clinical indications.

Glucokinase-MODY and HNF1A-MODY are the two most common subtypes of MODY. A mild subtype of MODY, glucokinase-MODY, might remain undiagnosed for decades, as the symptoms are generally mild or ...