Applied Clinical Trials Online3d
MITIGATE Trial Shows Uplizna Significantly Lowers Flare Risk, Glucocorticoid Dependence in IgG4-Related Disease
The Phase III MITIGATE trial demonstrated that Uplizna (inebilizumab) significantly reduces the risk of flares, lowers ...
AlphaGalileo1h
Preclinical and clinical studies on Qin-Zhu-Liang-Xue decoction: insights from network pharmacology and implications for atopic dermatitis treatment
Atopic dermatitis (AD) is a chronic inflammatory skin disease with high prevalence, especially in children. Current ...
Healio11d
TNF inhibitors do not significantly impact survival in lung, prostate colorectal cancer
TNF inhibitor use demonstrates no negative impact on survival among patients recently diagnosed with colorectal, lung or ...
ZME Science on MSN11d
Most Back Pain Treatments Don’t Work—Here’s What Actually Helps
Low back pain is one of the most common medical complaints in the world. Globally, over 600 million people suffer from it.
Nature10y
Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation
Asthma is a heterogeneous disorder, evidenced by distinct types of inflammation resulting in different responsiveness to therapy with glucocorticoids (GCs). Tumor necrosis factor α (TNFα) is ...
technologynetworks1mon
Glucocorticoid Exposure Impacts Neuronal Balance in Organoids
Infections, chemicals, stress – these environmental factors influence the risk of developing psychiatric or neurological disorders, especially if they occur before birth. The biological mechanisms ...
Hosted on MSN6mon
Steritas' Pediatric Glucocorticoid Toxicity Index applied by Alder Hey Children's NHS Foundation Trust and Liverpool Clinical Trials Centre in clinical trial to assess steroid ...
The pGTI is fast, accurate, and easy to implement.Use of the Steritas pGTI in this research initiative will allow researchers to assess the outcomes of intravenous and oral glucocorticoid ...