AskBio's approach meanwhile will involve using an adeno-associated virus (AAV) vector to deliver a gene for human glial cell line-derived neurotrophic factor (GDNF) into the neurons in the putamen.

Glial cells come in many forms, but three major types are currently recognized: astrocytes, oligodendrocytes and microglia. The first are primarily involved in creating the blood-brain barrier and ...

Ryotaro Hashizume and colleagues used the CRISPR-Cas9 gene editing system to cleave the third chromosome in previously generated trisomy 21 cell lines derived ... neurons and glial cells and ...

Glial cell line-derived neurotrophic factor (GDNF) is important for the development and maintenance of dopamine neurons. In rodent and primate models of Parkinson disease GDNF can have restorative ...

Glia are a non-neuronal category of cells that do not transmit electrical signals but still form an important part of the nervous system. Glial cells provide structural and other kinds of support ...

For example, the endothelial tissue that lines the human gastrointestinal ... neurons rarely divide. However, glial cells in the brain continue to divide throughout a mammal's adult life.