Every person carries two copies of most genes, with one version, or allele, coming from each parent. Even though these copies tend to be functionally redundant, conventional genetic theory dictates ...

2005;50(3):184-188. For example, in a white population, the most common deleterious allelic variant in the CFTR gene is CFTR delta F508 allele, resulting in the absence of a single amino acid ...

Somatic cells contain two alleles for every gene, with one allele provided by each parent of an organism. Often, it is impossible to determine which two alleles of a gene are present within an ...

Relative allele frequency is the percentage of all copies of a certain gene in a population that carry a specific allele. This is an accurate measurement of the amount of genetic variation in a ...

Implications for pathogenesis of genetic diseases: Validation of tissue-specific, maternal allele-specific methylation of the CHD7 gene suggests a potential mechanism for the paternal bias ...

A gene is a location on a chromosome where there ... matching chromosome passed on by the female gamete. 1 Homozygous for allele r rr Wrinkled 2 Homozygous for allele R RR Round Plants 2 and ...

The study demonstrated that cells in 14 brain regions, including multiple parts of the hypothalamus, which helps coordinate the endocrine system, specifically express the maternal allele for the gene ...

Heterozygous Describes an individual who has inherited two different alleles of the same gene from their parents Homozygous Describes an individual who has inherited the same allele for a gene ...

A single genetic switch could potentially treat a rare but severe childhood disorder. Prader-Willi Syndrome (PWS) affects approximately 1 in 15,000 newborns, causing insatiable hunger, obesity ...

A gene known as HbS was the center of a medical and evolutionary detective story that began in the middle 1940s in Africa. Doctors noticed that patients who had sickle cell anemia, a serious ...