Gastrulation is a process common to nearly all metazoan organisms during which an embryo with distinct tissue layers develops out of a seemingly unstructured assembly of cells referred to as ...

The study, "Selective utilization of glucose metabolism guides mammalian gastrulation," published in Nature, identifies two distinct waves of glucose utilization during mouse gastrulation.

When the authors blocked early steps in glucose metabolism using pharmacological inhibitors, the primitive streak failed to extend, demonstrating that dynamic glucose metabolism and gastrulation ...